Friday, April 29, 2011

What Is Mesothelioma?

Mesothelioma - What is it?
Mesothelioma is a cancer of the mesothelium, the membrane that surrounds the lungs, abdomen, and heart.

Mesothelioma primarily consists of three types.

-- Pleural Mesothelioma (cancer of the mesothelium surrounding the lungs)
-- Peritoneal Mesothelioma (cancer of the mesothelium surrounding the stomach)
-- Pericardial Mesothelioma (cancer of the mesothelium surrounding the heart)

It takes approximately 30 to 40 years for mesothelioma to develop and show its effects. This is the prime reason why mesothelioma is mostly seen in older patients, mostly male.

Mesothelioma is the most aggressive, painful, and fatal of all cancers.

Cause of Mesothelioma
The prime cause of mesothelioma is asbestos exposure. There are extremely rare instances when it is noticed that asbestos exposure is not the culprit, but even in these exceptionally rare instances it is possible that the person has been exposed to asbestos (indirectly) without even knowing it.

Even though mesothelioma is a very rare type of cancer, it is not so rare in those who have been exposed to asbestos.

Asbestos exposure could happen directly or indirectly.

Direct asbestos exposure happens when the person comes directly into contact with the asbestos fibers. Such persons could include asbestos mine workers, construction workers, building renovators, ship builders, ship breakers, clutch / brake liner workers / mechanics.

Indirect asbestos exposure happens when the person comes into indirect contact with asbestos / they could come into contact with any person who has had direct asbestos exposure. Such persons could include family and friends of those who have been directly exposed. Directly exposed persons have asbestos fibers embedded into their hair and clothing, passing the asbestos fibers to all those who come into contact with them.

A person need not be exposed to asbestos over long periods of time; even short term exposure could lead to mesothelioma.

What is Asbestos
Asbestos is a class of minerals appearing naturally in fibrous form. They are divided into two main groups - serpentine and amphibole. Chrysotile comes under the serpentine group, while actinolite, anthophylite, amosite, crocidolite and tremolite come under the amphibole group. Asbestos has been used commercially since the 1800s, but its use increased drastically since the 1940s right through the 1980s.

Asbestos found extensive usage in building material, insulation material, and many other uses due to its excellent properties of tensile strength, flexibility, and heat / corrosion / chemical resistance.

What is Asbestos Exposure
Asbestos exposure occurs when a person is subjected to the inhalation / ingestion of unseen microscopic asbestos fibers over a period of time. When inhaled, the asbestos fibers settle and get firmly lodged into the lungs.

Mesothelioma is the most common health effect caused by asbestos inhalation, but other health effects could include lung cancer and asbestosis. Mesothelioma is very different from these two, and should not be confused with lung cancer or asbestosis.

What is Pleural Mesothelioma
Pleural mesothelioma is the cancer affecting the lining that surrounds the lungs (pleura). It is the most common type of mesothelioma with over 80% of those diagnosed with mesothelioma suffering from it.

Signs and symptoms of pleural mesothelioma could include one or more of the following.

-- Chest pain (mild to severe)
-- Shortness of breath
-- Retention of excess fluid around the lungs
-- Constant cough (mild to severe)
-- Constant wheezing while breathing
-- Traces of blood in the sputum

What is Peritoneal Mesothelioma
Peritoneal mesothelioma is the cancer affecting the lining that surrounds the stomach. It is a type of mesothelioma that is not very common with just 10 to 20% of those diagnosed with mesothelioma suffering from it.

Signs and symptoms of peritoneal mesothelioma could include one or more of the following.

-- Constant pain in the abdomen (mild to severe)
-- Retention of excess fluid around the stomach
-- Tissue lumps in the abdomen
-- Constant diarrhea or constipation
-- Sudden unexplained weight loss
-- Nausea

What is Pericardial Mesothelioma
Pericardial mesothelioma is the cancer affecting the lining that surrounds the heart. It is the rarest type of mesothelioma with extremely few of those diagnosed with mesothelioma suffering from it.

Signs and symptoms of pericardial mesothelioma could include one or more of the following.

-- Chest pain (mild to severe)
-- Shortness of breath
-- Heart palpitations
-- Constant cough (mild to severe)

Mesothelioma Diagnosis
The diagnosis of mesothelioma is not easy since the symptoms overlap with many other common ailments such as pneumonia, the common cold, and seasonal allergies.

After reviewing the patients complete medical history, the physician / surgeon will ask for further tests to be conducted if he suspects mesothelioma.

The best way to determine mesothelioma is through imaging tests which could include one or more of the following.

-- X-rays
-- CAT / CT Scan
-- MRI Scan
-- PET Scan

Performing a biopsy is another way of confirming mesothelioma. These could include either a Thoracoscopy or a Peritoneoscopy.

Treating Mesothelioma
Treatment will depend entirely on the results of the tests performed. The physician / surgeon will take into consideration at what stage the cancer has been diagnosed, and the patients age / health.

The most common type of treatment for mesothelioma is surgery, followed by radiation therapy, and chemotherapy. A combination of these treatments could be used depending on the situation.

A total cure for mesothelioma is not possible, with all treatments used to increase the life expectancy of the patient.

Is Mesothelioma Fatal
Yes. Mesothelioma is fatal, always. It takes in between 30 to 40 years after initial exposure for mesothelioma to surface. Due to the nature of the disease, mesothelioma is almost always diagnosed when it has spread to incurable levels. At this stage, the patient will survive for just a further 12 to 18 months with treatment.

Better Cures / Treatment for Mesothelioma
There is currently a lot of research / focus on new ways and techniques to cure mesothelioma. Many treatments are at present undergoing clinical trials with promising results. If you suspect asbestos exposure in the past, consult your physician / surgeon. If diagnosed with mesothelioma, the surgeon will guide you on the latest techniques that are undergoing trial. You could volunteer to take part in these trials. All these modern treatments use the latest technologies and equipment available, but will still not guarantee total cure. Yes, what it could possible do is increase the survival rate from a mere 12 to 18 months after diagnosis to a much better 5 to 10 years. During this time (5 to 10 years from now) better options could be available, further prolonging your life, possibly even curing the mesothelioma totally.

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